Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CASP14 | P31944 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035084 | 0.95 | CTSV (0.51) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035395 | 0.95 | TP53 (0.50) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL3056423 | 0.88 | TP53 (0.63) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035411 | 0.87 | TP53 (0.50) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035379 | 0.81 | PRKCQ (0.49) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035485 | 0.81 | TP53 (0.56) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6414132 | 0.80 | MAPT (0.55) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035092 | 0.80 | MAPT (0.47) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035402 | 0.80 | MAPT (0.47) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL26035094 | 0.79 | MAPT (0.53) | MEN1KMT2ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159248-A1 | RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2023-08-24 | — | — | WO | disclosed |