Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035379 | 0.95 | PRKCQ (0.49) | MAPTTP53SMN1; SMN2POLBPRKCQ | |
| SCHEMBL26035092 | 0.89 | MAPT (0.47) | MAPTTP53SMN1; SMN2POLBPRKCQ | |
| SCHEMBL26035089 | 0.86 | MAPT (0.47) | MAPTTP53SMN1; SMN2POLBPRKCQ | |
| SCHEMBL3056423 | 0.83 | TP53 (0.63) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL26035395 | 0.82 | TP53 (0.50) | MAPTTP53SMN1; SMN2POLBPRKCQ | |
| SCHEMBL26035084 | 0.80 | CTSV (0.51) | MAPTTP53SMN1; SMN2POLBPRKCQ | |
| SCHEMBL26035448 | 0.80 | MEN1 (0.53) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL26035098 | 0.79 | MAPT (0.51) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL26035474 | 0.79 | EGFR (0.54) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL26035496 | 0.79 | MAPT (0.57) | MAPTTP53SMN1; SMN2POLBCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159248-A1 | RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2023-08-24 | — | — | WO | disclosed |