Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998547 | 0.86 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL26035826 | 0.86 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL16998553 | 0.84 | KDM4C (0.43) | KDM4CDHFRNPC1RAB9AL3MBTL1 | |
| SCHEMBL16998565 | 0.81 | KDM4C (0.44) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL12380457 | 0.70 | ICAM1 (0.39) | KDM4CDHFRNPC1RAB9APTPN1 | |
| SCHEMBL26036026 | 0.69 | GHSR (0.32) | — | |
| SCHEMBL12306794 | 0.67 | MEN1 (0.37) | KDM4CNPC1RAB9APTPN1L3MBTL1 | |
| SCHEMBL16998566 | 0.67 | PIK3CA (0.33) | NPC1RAB9A | |
| SCHEMBL26036028 | 0.67 | KDM4C (0.43) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL19788463 | 0.66 | PIK3CD (0.38) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3058960-B1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | HAMAMATSU PHOTONICS KK (JP) | 2023-08-30 | — | — | EP | disclosed |