Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998553 | 0.92 | KDM4C (0.43) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL26035826 | 0.87 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL16998547 | 0.87 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL26036028 | 0.87 | KDM4C (0.43) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL16998563 | 0.83 | KDM4C (0.48) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL26036024 | 0.81 | KDM4C (0.34) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL30935589 | 0.77 | KDM4C (0.45) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL18106022 | 0.76 | KDM4C (0.44) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL21070800 | 0.73 | KDM4C (0.42) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL2568655 | 0.73 | KDM4C (0.47) | KDM4CNPC1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872928-B2 | Diagnostic agent for therapeutic effect on cancer | HAMAMATSU PHOTONICS K.K. (JP) | 2018-01-23 | — | — | US | disclosed |
| US-9598399-B2 | Compound suitable for detection of mitochondrial complex-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2017-03-21 | — | — | US | disclosed |
| US-9598399-B2 | Compound suitable for detection of mitochondrial complex-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | HAMAMATSU PHOTONICS K.K. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | HAMAMATSU PHOTONICS K.K. (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3058960-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | Hamamatsu Photonics K.K. (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | NOC2L, NOP56, NPM1 | KDM4C 3829/4885NPC1 187/4885RAB9A 3364/4885 |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | MT-ND1, MT-CO1, UQCRC1 | KDM4C 3605/4885NPC1 508/4885RAB9A 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.