SCHEMBL26037709

SCHEMBL26037709

C1=CC(c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5oc6c(-c7ccc(-c8ccc9ccccc9c8)cc7)cccc6c45)n3)cc2)=CCC1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.34
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 3/20 0.32
HSD17B10 Q99714 2/20 0.32
ALOX5 P09917 1/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 3/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25651349 0.96 PRKDC (0.34) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL25832501 0.96 PRKDC (0.34) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL24314906 0.93 ALOX5 (0.34) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL24314925 0.93 ALOX5 (0.34) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL24314784 0.93 ALOX5 (0.34) PRKDCALOX5TSHR
SCHEMBL23820527 0.93 PRKDC (0.36) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL26892986 0.92 ALOX5 (0.34) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL24973300 0.91 PRKDC (0.35) PRKDCALOX5
SCHEMBL24972645 0.89 ALDH1A1 (0.33) PRKDCALDH1A1KDM4EHSD17B10ALOX5
SCHEMBL22174524 0.88 ALOX5 (0.36) PRKDCALDH1A1KDM4EHSD17B10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed