Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349897 | 0.84 | KDM4E (0.44) | PKMGABRA5JMJD6SCN9AALDH1A1 | |
| SCHEMBL25999611 | 0.80 | CCNE1 (0.40) | PKMGABRA5L3MBTL1MEN1KMT2A | |
| SCHEMBL17517052 | 0.72 | BAZ2B (0.41) | BAZ2BBRD4L3MBTL1MEN1KMT2A | |
| SCHEMBL24799262 | 0.72 | BAZ2B (0.51) | BAZ2BBRD4L3MBTL1MEN1KMT2A | |
| SCHEMBL27239565 | 0.72 | CDK2 (0.45) | — | |
| SCHEMBL17473215 | 0.71 | PKM (0.37) | PKMBAZ2BBRD4L3MBTL1ALDH1A1 | |
| SCHEMBL31667472 | 0.70 | CA12 (0.39) | PKMGABRA5L3MBTL1JMJD6MEN1 | |
| SCHEMBL2737317 | 0.69 | BAZ2B (0.46) | BAZ2BBRD4L3MBTL1MEN1KMT2A | |
| SCHEMBL8568508 | 0.69 | SMN1; SMN2 (0.56) | BAZ2BL3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL27258704 | 0.69 | JMJD6 (0.32) | PKMJMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154426-A1 | CDK INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |