Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982616 | 0.91 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8982607 | 0.85 | THRB (0.53) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29997084 | 0.85 | THRB (0.53) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10493437 | 0.84 | TSHR (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17034383 | 0.84 | ALDH1A1 (0.53) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6281230 | 0.82 | THRB (0.54) | THRBALDH1A1SMN1; SMN2TDP1LMNA | |
| SCHEMBL434163 | 0.82 | THRB (0.65) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17036924 | 0.82 | THRB (0.61) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL22667631 | 0.81 | ALDH1A1 (0.61) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL25501725 | 0.81 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265346-A1 | LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-08-24 | — | — | US | disclosed |