Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | LPL | P06858 | 9/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033366 | 0.81 | EGFR (0.55) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL30126803 | 0.81 | EGFR (0.52) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL1585479 | 0.80 | EGFR (0.54) | EGFR | |
| SCHEMBL30127458 | 0.78 | EGFR (0.52) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL30926304 | 0.78 | EGFR (0.52) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL21756263 | 0.78 | EGFR (0.52) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL20311704 | 0.76 | EGFR (0.46) | EGFRLPLLIPGPRMT5WDR77 | |
| Ammonia Solution, Strong SCHEMBL28597121 | 0.75 | LPL (0.44) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL15254803 | 0.74 | EGFR (0.46) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL1584960 | 0.73 | EGFR (0.58) | EGFRHIF1AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |