Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 8/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033366 | 0.88 | EGFR (0.55) | EGFRIDO1TDO2LPLLIPG | |
| SCHEMBL26043142 | 0.76 | EGFR (0.52) | EGFRIDO1TDO2LPLLIPG | |
| SCHEMBL26322019 | 0.74 | LIPG (0.42) | EGFRLPLLIPGPRMT5WDR77 | |
| SCHEMBL30926304 | 0.74 | EGFR (0.52) | EGFRIDO1TDO2LPLLIPG | |
| SCHEMBL1585479 | 0.73 | EGFR (0.54) | EGFR | |
| SCHEMBL18682054 | 0.73 | LIPG (0.59) | LPLLIPG | |
| SCHEMBL19022053 | 0.72 | LPL (0.50) | LPLLIPGHIF1A | |
| SCHEMBL30127458 | 0.71 | EGFR (0.52) | EGFRIDO1TDO2LPLLIPG | |
| SCHEMBL30126803 | 0.71 | EGFR (0.52) | EGFRIDO1TDO2LPLLIPG | |
| SCHEMBL21756263 | 0.71 | EGFR (0.52) | EGFRIDO1TDO2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252293-B1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC (US) | 2018-06-27 | — | — | EP | disclosed |