SCHEMBL2604422

SCHEMBL2604422

Cc1cccc(-n2c3ccc(-c4ccc5c(c4)c4ccc(-n6c7ccc(C(C)(C)C)cc7c7cc(C(C)(C)C)ccc76)cc4n5-c4cccc(C)c4)cc3c3ccc(-n4c5ccc(C(C)(C)C)cc5c5cc(C(C)(C)C)ccc54)cc32)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.39
OPRD1 P41143 7/20 0.36
OPRM1 P35372 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
MAT2A P31153 1/20 0.35
NOTUM Q6P988 2/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
NR3C1 P04150 1/20 0.33
GAA P10253 1/20 0.33
OPRK1 P41145 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021221 0.97 OPRD1 (0.38) SERPINE1OPRD1OPRM1ALDH1A1MAPT
SCHEMBL2604421 0.93 SERPINE1 (0.41) SERPINE1OPRD1OPRM1ALDH1A1MAPT
SCHEMBL24797315 0.91 TDP1 (0.39) SERPINE1OPRD1OPRM1ALDH1A1TDP1
SCHEMBL2604423 0.88 KDM4E (0.42) SERPINE1OPRD1ALDH1A1MAPTMAT2A
SCHEMBL10206206 0.88 TDP1 (0.41) OPRD1OPRM1ALDH1A1TDP1MAT2A
SCHEMBL2607410 0.88 TDP1 (0.43) OPRD1OPRM1ALDH1A1TDP1NOTUM
SCHEMBL13761988 0.86 SERPINE1 (0.36) SERPINE1OPRD1OPRM1ALDH1A1MAPT
SCHEMBL13761987 0.86 SERPINE1 (0.36) SERPINE1OPRD1OPRM1ALDH1A1MAPT
SCHEMBL16171497 0.86 KDM4E (0.47) SERPINE1ALDH1A1MAPTMAT2AKDM4E
SCHEMBL12394526 0.85 KDM4E (0.42) OPRD1OPRM1ALDH1A1MAPTMAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed