⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712254 | 1.00 | — | — | |
| SCHEMBL24996930 | 0.91 | MAPK1 (0.31) | — | |
| SCHEMBL22098680 | 0.81 | HSD11B1 (0.36) | — | |
| SCHEMBL10129912 | 0.80 | — | — | |
| SCHEMBL9963382 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL761435 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL13222181 | 0.78 | — | — | |
| SCHEMBL14298073 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL8079753 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL20962519 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144297-A1 | RIFAMYCIN DERIVATIVES FOR THE TREATMENT OF DISEASES | BioVersys AG (CH) | 2023-08-03 | — | — | WO | disclosed |