SCHEMBL26044945

SCHEMBL26044945

CCCCOc1ccc(-c2ccc(-c3ccc(CCCC)cc3)c(F)c2F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.51
MEN1 O00255 1/20 0.51
USP2 O75604 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
MAPK1 P28482 1/20 0.51
CASP1 P29466 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SLCO1B3 Q9NPD5 1/20 0.51
SLCO1B1 Q9Y6L6 1/20 0.51
CYP2D6 P10635 3/20 0.46
CYP1A2 P05177 2/20 0.44
CYP19A1 P11511 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
S1PR1 P21453 3/20 0.44
S1PR3 Q99500 2/20 0.44
MPL P40238 2/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26044942 0.97 LMNA (0.49) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9495426 0.96 MEN1 (0.55) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9494645 0.95 CYP3A4 (0.57) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9563702 0.94 CYP3A4 (0.53) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9494790 0.94 CYP3A4 (0.56) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9494683 0.94 MEN1 (0.59) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9493277 0.94 ALDH1A1 (0.49) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL15581208 0.93 CYP3A4 (0.46) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9497822 0.93 MEN1 (0.58) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL9493415 0.93 LMNA (0.55) CYP3A4MEN1USP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed