SCHEMBL26046673

SCHEMBL26046673

Cc1ccc(-c2ccc(-c3ccc(S)cc3)c(C)c2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PTGS2 P35354 5/20 0.33
COMT P21964 1/20 0.33
IDO1 P14902 1/20 0.32
PTGS1 P23219 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
MAOB P27338 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26045498 0.84 ACHE (0.36) ACHETDP1PTGS2COMTIDO1
SCHEMBL862135 0.82 ACHE (0.50) ACHETDP1IDO1CYP2D6CYP2C9
SCHEMBL12960035 0.82 ACHE (0.50) ACHETDP1IDO1CYP2D6CYP2C9
SCHEMBL15929643 0.79 TDP1 (0.36) ACHETDP1PTGS2PTGS1MEN1
SCHEMBL72612 0.79
SCHEMBL13377972 0.78 NPC1 (0.48) ACHETDP1MEN1NPC1RAB9A
SCHEMBL26742420 0.77 ESR2 (0.41) TDP1MEN1NPC1RAB9AKMT2A
SCHEMBL6722376 0.76 ACHE (0.38) ACHETDP1PTGS2COMTPTGS1
SCHEMBL2209060 0.76 ACHE (0.57) ACHETDP1IDO1CA9
SCHEMBL6514380 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed