SCHEMBL6722376

SCHEMBL6722376

Cc1ccc(-c2ccc(C)c(C)c2C)cc1.Cc1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TDP2 O95551 1/20 0.38
NSD2 O96028 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PAX8 Q06710 1/20 0.38
POLB P06746 1/20 0.36
HPRT1 P00492 1/20 0.34
PTGS2 P35354 4/20 0.33
COMT P21964 1/20 0.33
PTGS1 P23219 1/20 0.33
ADORA3 P0DMS8 2/20 0.33
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
KIF11 P52732 1/20 0.32
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27975217 0.84 ESR2 (0.45) TDP1TDP2NSD2HSP90AA1PAX8
SCHEMBL28134118 0.79 ALDH1A1 (0.40) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL13377970 0.79 ADORA3 (0.42) ACHETDP1POLBHPRT1PTGS2
SCHEMBL28235447 0.79 TDP2 (0.46) ACHETDP1TDP2NSD2HSP90AA1
SCHEMBL28219529 0.79 SENP1 (0.46) ACHE
SCHEMBL30804714 0.78 ESR2 (0.48) ACHETDP2NSD2HSP90AA1PAX8
SCHEMBL2400343 0.78 ESR2 (0.48) ACHETDP2NSD2HSP90AA1PAX8
SCHEMBL13377972 0.78 NPC1 (0.48) ACHETDP1POLBHPRT1
SCHEMBL11206611 0.77 POLB (0.67) ACHETDP1POLB
SCHEMBL18155416 0.77 PTGS2 (0.40) ACHETDP1TDP2NSD2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728367-A1 RIGID FOAMS Econic Technologies Limited (GB) 2020-10-28 EP claimed
EP-4114887-A1 METHOD OF PREPARATION OF A POLYOL BLOCK COPOLYMER Econic Technologies Limited (GB) 2023-01-11 EP disclosed
EP-4114886-A1 A POLYOL BLOCK COPOLYMER Econic Technologies Limited (GB) 2023-01-11 EP disclosed
EP-3994197-A1 A POLYOL BLOCK COPOLYMER, COMPOSITIONS AND PROCESSES THEREFOR Econic Technologies Limited (GB) 2022-05-11 EP disclosed
EP-3983472-A1 A POLYOL BLOCK COPOLYMER, COMPOSITIONS AND PROCESSES THEREFOR Econic Technologies Limited (GB) 2022-04-20 EP disclosed
WO-2021176212-A1 METHOD OF PREPARATION OF A POLYOL BLOCK COPOLYMER ECONIC TECHNOLOGIES LTD (GB) 2021-09-10 WO disclosed
WO-2020222019-A1 A POLYOL BLOCK COPOLYMER, COMPOSITIONS AND PROCESSES THEREFOR ECONIC TECHNOLOGIES LTD (GB) 2020-11-05 WO disclosed
WO-2020222018-A1 A POLYOL BLOCK COPOLYMER, COMPOSITIONS AND PROCESSES THEREFOR ECONIC TECHNOLOGIES LTD (GB) 2020-11-05 WO disclosed
US-20040229046-A1 Aqueous vacuum-forming laminating adhesive composition containing polyether based plasticizers PPG INDUSTRIES OHIO, INC. 2004-11-18 US disclosed
US-20040014830-A1 Composition for use in flexible polyurethane foams FERRO CORPORATION (US) 2004-01-22 US disclosed
US-20030212235-A1 Reactive hot melt adhesive NOWICKI JAMES W (US) 2003-11-13 US disclosed