SCHEMBL2604680

SCHEMBL2604680

C=C(C)C(=O)Oc1ccc2c(c1)Cc1cc(OC(=O)C(=C)C)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
ATM Q13315 1/20 0.48
ELANE P08246 1/20 0.47
MAPT P10636 4/20 0.47
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
METAP1 P53582 2/20 0.41
HSD17B1 P14061 1/20 0.41
CYP1A2 P05177 1/20 0.39
ADRA2A P08913 1/20 0.39
MAOA P21397 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR2B P41595 1/20 0.39
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TDP2 O95551 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258843 0.90 KMT2A (0.48) KMT2AATMELANEMAPTRAB9A
SCHEMBL783519 0.90 KMT2A (0.51) KMT2AATMELANEMAPTRAB9A
SCHEMBL2604683 0.89 KMT2A (0.40) KMT2AATMELANEMAPTRAB9A
SCHEMBL31122376 0.86 ELANE (0.49) KMT2AATMELANEMAPTRAB9A
SCHEMBL21663252 0.84 KMT2A (0.46) KMT2AATMELANEMAPTRAB9A
SCHEMBL12216192 0.84 KMT2A (0.49) KMT2AATMELANEMAPTMETAP1
SCHEMBL2604684 0.83 MAPT (0.40) KMT2AMAPTRAB9ANPC1METAP1
SCHEMBL805425 0.83 KMT2A (0.46) KMT2AATMELANEMAPTRAB9A
SCHEMBL6536539 0.82 MAPT (0.53) KMT2AELANEMAPTRAB9ANPC1
SCHEMBL24411791 0.82 KMT2A (0.48) KMT2AATMELANEMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160342029-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-24 US disclosed
US-20160342029-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-24 US disclosed
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT JNC PETROCHEMICAL CORPORATION (JP) 2012-04-19 US disclosed
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT JNC PETROCHEMICAL CORPORATION (JP) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT KLK3, PDE7A, FZD7 KMT2A 3313/4885ATM 737/4885ELANE 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.