SCHEMBL783519

SCHEMBL783519

C=C(C)C(=O)Oc1ccc2c(c1)CCc1cc(OC(=O)C(=C)C)ccc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
ATM Q13315 2/20 0.51
ELANE P08246 1/20 0.47
KDM4E B2RXH2 3/20 0.40
GLA P06280 2/20 0.40
MAPT P10636 5/20 0.40
RAB9A P51151 4/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 3/20 0.39
MAPK14 Q16539 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
MEN1 O00255 2/20 0.37
ALPL P05186 1/20 0.37
CLK1 P49759 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MIF P14174 2/20 0.36
CYP26A1 O43174 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL805425 0.93 KMT2A (0.46) KMT2AATMELANEKDM4EGLA
SCHEMBL24411791 0.91 KMT2A (0.48) KMT2AATMELANEKDM4EGLA
SCHEMBL2604680 0.90 KMT2A (0.48) KMT2AATMELANEKDM4EMAPT
SCHEMBL24411792 0.88 KMT2A (0.42) KMT2AATMELANEKDM4EGLA
SCHEMBL802742 0.87 KMT2A (0.41) KMT2AATMELANEKDM4EGLA
SCHEMBL10457802 0.87 KMT2A (0.41) KMT2AATMELANEKDM4EGLA
SCHEMBL24411790 0.87 KMT2A (0.41) KMT2AATMELANEKDM4EGLA
SCHEMBL24411882 0.85 KMT2A (0.40) KMT2AATMELANEKDM4EGLA
SCHEMBL24411793 0.85 ATM (0.40) KMT2AATMELANEKDM4EGLA
SCHEMBL24411880 0.84 HSD17B1 (0.40) KMT2AATMELANEKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906662-B1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2020-04-01 EP disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20150340612-A1 UV EMITTERS COMPRISING A MULTIPLE BOND MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340612-A1 UV EMITTERS COMPRISING A MULTIPLE BOND MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150270489-A1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-20150270489-A1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-20150062518-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE TOYO GOSEI CO., LTD. (JP) 2015-03-05 US disclosed
WO-2014106520-A1 UV EMITTERS COMPRISING A MULTIPLE BOND MERCK PATENT GMBH (DE) 2014-07-10 WO disclosed
EP-2432851-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
EP-2432851-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
EP-2432851-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2012-03-28 EP disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120069289-A1 LIQUID CRYSTAL DISPLAY LPXN, VCL, ACP3 KMT2A 3141/4885ATM 2466/4885ELANE 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.