SCHEMBL2604707

SCHEMBL2604707

CCCCCC1CCC(c2ccc(OCC)c(F)c2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
OPRL1 P41146 8/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM1A O60341 2/20 0.33
SCN9A Q15858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3269906 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL30450387 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL7728041 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL7728037 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL7728045 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL1574929 1.00 MAPT (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL8455394 0.99 MAPT (0.38) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL9406329 0.99 MAPT (0.38) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL9405746 0.99 MAPT (0.38) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL8455398 0.99 MAPT (0.38) MAPTGAAMEN1KMT2AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116254121-A Negative liquid crystal mixture, display panel, display device and driving method 北京京东方显示技术有限公司 2023-06-13 CN claimed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-20230323207-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-7026021-B2 Fluorinated heterocycles and their use in liquid-crystal mixtures MERCK PATENT GMBH (DE) 2006-04-11 US disclosed
US-6955838-B2 Fluorinated polycycles and their use in liquid-crystal mixtures CLARIANT INTERNATIONAL LTD. (CH) 2005-10-18 US disclosed
US-20050098762-A1 4,6,7-Trifluoro-benzo[b]naphtho[2,3-d]furan derivatives MERCK PATENT GMBH (DE) 2005-05-12 US disclosed
US-6887533-B2 Fluorinated oxaanthracenes and their use in liquid-crystal mixtures CLARIANT INTERNATIONAL, LTD. (CH) 2005-05-03 US disclosed
US-20050056812-A1 Fluorinated heterocycles and their use in liquid-crystal mixtures MERCK PATENT GMBH (DE) 2005-03-17 US disclosed
US-5980778-A STABILITY, COMPATIBILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0768361-A1 Liquid crystal composition and liquid crystal display element comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-04-16 EP disclosed
US-5279764-A Dihalogenobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US disclosed
EP-0364538-A1 DIFLUOROBENZOL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-04-25 EP disclosed
WO-1989008633-A1 DIFLUOROBENZOL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 MAPT 1064/4885GAA 4790/4885MEN1 3631/4885
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used SFXN1, SFXN3, SIK3 MAPT 4455/4885GAA 4879/4885MEN1 3058/4885
US-20050056812-A1 Fluorinated heterocycles and their use in liquid-crystal mixtures CHRM1, SCO2, CHRM2 MAPT 3342/4885GAA 4835/4885MEN1 121/4885
US-20050098762-A1 4,6,7-Trifluoro-benzo[b]naphtho[2,3-d]furan derivatives CCNT1, CBR1, SCO2 MAPT 1561/4885GAA 4637/4885MEN1 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.