Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450387 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL7728041 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL2604707 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL7728037 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL7728045 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL1574929 | 1.00 | MAPT (0.36) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL8455394 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL9406329 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL9405746 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AOPRL1 | |
| SCHEMBL8455398 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110373210-B | Difluoroethoxy-containing liquid crystal compound and composition thereof | 西安近代化学研究所 | 2021-12-21 | — | — | CN | disclosed |
| EP-2199270-B1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2016-05-25 | — | — | EP | disclosed |
| US-20140362335-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | LC VISION, LLC (US) | 2014-12-11 | — | — | US | disclosed |
| US-8834742-B2 | Polymer-doped vertically-aligned nematic liquid crystals | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-16 | — | — | US | disclosed |
| US-8580142-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20120105791-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | NATIONAL SCIENCE FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-20100328600-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| EP-2199270-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-5980778-A | STABILITY, COMPATIBILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0768361-A1 | Liquid crystal composition and liquid crystal display element comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0364538-A1 | DIFLUOROBENZOL DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989008633-A1 | DIFLUOROBENZOL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100328600-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, MARK3, CCND3 | MAPT 271/4885GAA 4848/4885MEN1 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.