Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339938 | 1.00 | TDP1 (0.67) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL31734100 | 0.93 | TDP1 (0.70) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL16561497 | 0.91 | TDP1 (0.60) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL4570319 | 0.90 | TDP1 (0.70) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL2606463 | 0.87 | PTGS1 (0.51) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL11239419 | 0.86 | TDP1 (0.70) | TDP1L3MBTL1LMNAALDH1A1ESR1 | |
| SCHEMBL12111438 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL14216634 | 0.86 | TDP1 (0.58) | TDP1L3MBTL1ATMLMNAPBRM1 | |
| SCHEMBL1534235 | 0.86 | ATM (0.62) | TDP1L3MBTL1ATMLMNAALDH1A1 | |
| SCHEMBL16561536 | 0.85 | TDP1 (0.49) | TDP1L3MBTL1ATMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9454077-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-09-27 | — | — | US | disclosed |
| US-9454077-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160231649-A1 | Photochemical Methods and Photoactive Compounds for Modifying Surfaces | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | disclosed |
| US-20160231649-A1 | Photochemical Methods and Photoactive Compounds for Modifying Surfaces | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | disclosed |
| US-8957225-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-02-17 | — | — | US | disclosed |
| US-8957225-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-02-17 | — | — | US | disclosed |
| US-20120178650-A1 | PHOTOCHEMICAL METHODS AND PHOTOACTIVE COMPOUNDS FOR MODIFYING SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120178650-A1 | PHOTOCHEMICAL METHODS AND PHOTOACTIVE COMPOUNDS FOR MODIFYING SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-07-12 | — | — | US | disclosed |
| US-8158832-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158832-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100099580-A1 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100099580-A1 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-04-22 | — | — | US | disclosed |
| WO-2008054398-A2 | PHOTOCHEMICAL METHODS AND PHOTOACTIVE COMPOUNDS FOR MODIFYING SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178650-A1 | PHOTOCHEMICAL METHODS AND PHOTOACTIVE COMPOUNDS FOR MODIFYING SURFACES | DDT, SELE, DNMT1 | TDP1 2073/4885L3MBTL1 2712/4885ATM 3186/4885 |
| US-20100099580-A1 | Photochemical methods and photoactive compounds for modifying surfaces | DDT, SELE, DNMT1 | TDP1 2073/4885L3MBTL1 2712/4885ATM 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.