Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604741 | 0.87 | TDP1 (0.67) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL31339938 | 0.87 | TDP1 (0.67) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL23018871 | 0.85 | ATM (0.64) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL20696554 | 0.85 | ATM (0.64) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL15264145 | 0.85 | MAPT (0.64) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL1865894 | 0.81 | CYP4F2 (0.50) | MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31734100 | 0.81 | TDP1 (0.70) | TDP1ATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL16561497 | 0.79 | TDP1 (0.60) | PTGS1PTGS2TDP1ATML3MBTL1 | |
| SCHEMBL4570319 | 0.78 | TDP1 (0.70) | TDP1ATML3MBTL1SMN1; SMN2ALDH1A1 | |
| Benzophenone SCHEMBL1781970 | 0.76 | ALDH1A1 (0.67) | PTGS1PTGS2TDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158832-B2 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100099580-A1 | Photochemical methods and photoactive compounds for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099580-A1 | Photochemical methods and photoactive compounds for modifying surfaces | DDT, SELE, DNMT1 | PTGS1 2536/4885PTGS2 2080/4885TDP1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.