Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604746 | 0.86 | SETD7 (0.51) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL25616981 | 0.84 | PTAFR (0.43) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL14273801 | 0.82 | SETD7 (0.36) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL2116710 | 0.77 | SETD7 (0.51) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL6988373 | 0.71 | HRH1 (0.61) | PTAFRHRH1CHRM2HTR2AOPRK1 | |
| SCHEMBL27300170 | 0.70 | SETD7 (0.48) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL6990036 | 0.68 | SETD7 (0.48) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL7092907 | 0.67 | SETD7 (0.56) | PTAFRHRH1SETD7CHRM2HTR1A | |
| Alcaftadine SCHEMBL29378093 | 0.67 | SETD7 (0.52) | PTAFRHRH1SETD7CHRM2HTR1A | |
| SCHEMBL5060512 | 0.67 | SETD7 (0.52) | PTAFRHRH1SETD7CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065605-A1 | TREATMENTS OF OCULAR ALLERGY WITH ALCAFTADINE | VISTAKON PHARMACEUTICALS, LLC | 2017-03-09 | — | — | US | disclosed |
| US-20170065605-A1 | TREATMENTS OF OCULAR ALLERGY WITH ALCAFTADINE | VISTAKON PHARMACEUTICALS, LLC | 2017-03-09 | — | — | US | disclosed |
| US-20120094978-A1 | Ocular Allergy Treatments | PARASRAMPURIA JAGDISH (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065605-A1 | TREATMENTS OF OCULAR ALLERGY WITH ALCAFTADINE | CCL11, HRH2, IL5 | PTAFR 293/4885HRH1 7/4885SETD7 2348/4885 |
| US-20120094978-A1 | Ocular Allergy Treatments | HRH2, CMA1, TPSAB1 | PTAFR 290/4885HRH1 9/4885SETD7 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.