Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26048379 | 1.00 | NLRP3 (0.44) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL25434999 | 1.00 | NLRP3 (0.44) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL26048853 | 1.00 | NLRP3 (0.44) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL26048790 | 0.93 | NLRP3 (0.42) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL26048788 | 0.93 | NLRP3 (0.42) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL26048328 | 0.93 | NLRP3 (0.42) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL25430440 | 0.90 | NLRP3 (0.41) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL25434565 | 0.90 | NLRP3 (0.46) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL31513515 | 0.90 | NLRP3 (0.46) | NLRP3CHRNA7NPSR1TP53ALDH1A1 | |
| SCHEMBL26048422 | 0.90 | NLRP3 (0.46) | NLRP3CHRNA7NPSR1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158708-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-08-24 | — | — | WO | disclosed |