Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991551 | 0.88 | TDP1 (0.54) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL12492829 | 0.88 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL17129602 | 0.88 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL2934574 | 0.86 | TDP1 (0.52) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL9478194 | 0.86 | L3MBTL1 (0.56) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL17991550 | 0.86 | NOTUM (0.59) | ALDH1A1L3MBTL1TDP1NOTUMMAPT | |
| SCHEMBL15574247 | 0.84 | MAPT (0.62) | ALDH1A1MAPTLMNAGAATSHR | |
| SCHEMBL8398812 | 0.84 | KDM4E (0.53) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| SCHEMBL18031268 | 0.84 | MAPT (0.62) | MAPTLMNATSHRCA12CA1 | |
| SCHEMBL31401228 | 0.84 | TSHR (0.51) | ALDH1A1TDP1TTRTSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Apollo Therapeutics Limited (GB) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CSNK1A1, CSNK1D, CSNK2A1 | ALDH1A1 2913/4885L3MBTL1 3250/4885TDP1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.