Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012587 | 0.73 | EPHX1 (0.36) | — | |
| SCHEMBL28111365 | 0.72 | DNM1 (0.38) | ALDH1A1TDP1DNM1 | |
| SCHEMBL8813653 | 0.69 | — | — | |
| SCHEMBL56652 | 0.68 | LMNA (0.50) | ALDH1A1TDP1DNM1 | |
| SCHEMBL23484289 | 0.67 | TSHR (0.39) | — | |
| SCHEMBL13974336 | 0.67 | DNM1 (0.33) | ALDH1A1TDP1DNM1 | |
| SCHEMBL18256105 | 0.66 | ACE2 (0.43) | ALDH1A1TDP1DNM1 | |
| SCHEMBL24831364 | 0.66 | LMNA (0.43) | ALDH1A1TDP1DNM1 | |
| SCHEMBL18286447 | 0.66 | ACE2 (0.43) | ALDH1A1TDP1DNM1 | |
| SCHEMBL31521551 | 0.66 | LMNA (0.56) | ALDH1A1TDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223309-A1 | COMBINATION THERAPY WITH CONTROLLED-RELEASE CNP AGONISTS | Ascendis Pharma Growth Disorders A/S (DK) | 2023-08-09 | — | — | EP | disclosed |