SCHEMBL26049263

SCHEMBL26049263

Cc1cc(CCC(=O)OCCOCCOCCOC(=O)CCc2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.63
YWHAG P61981 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
IAPP P10997 3/20 0.43
ALOX5 P09917 3/20 0.43
OR51E2 Q9H255 1/20 0.42
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
P2RY12 Q9H244 1/20 0.40
FFAR4 Q5NUL3 2/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12246761 0.88 APP (0.83) APPYWHAGTDP1ESR1ESR2
SCHEMBL1549436 0.88 CYP4F2 (0.61) APPYWHAGESR1ESR2CYP4F2
SCHEMBL27558178 0.87 APP (0.58) APPYWHAGTDP1ESR1ESR2
SCHEMBL12626243 0.84 APP (0.58) APPYWHAGTDP1ESR1ESR2
SCHEMBL18269500 0.83 ALOX5 (0.53) APPESR1ESR2CYP4F2CYP4A11
SCHEMBL2045372 0.83 ALOX5 (0.49) APPTDP1ESR1CYP4F2CYP4A11
SCHEMBL18998959 0.82 APP (0.73) APPYWHAGTDP1IAPPALOX5
SCHEMBL7116001 0.81 APP (0.58) APPYWHAGTDP1CYP4F2CYP4A11
SCHEMBL30077234 0.81 APP (0.58) APPYWHAGTDP1CYP4F2CYP4A11
SCHEMBL12626221 0.81 APP (0.51) APPYWHAGTDP1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158225-A1 SELF-HEALING AND RECYCLABLE POLYURETHANE POLYMER 한국화학연구원 2023-08-24 WO disclosed