Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 8/20 | 0.47 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | AGL | P35573 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340416 | 0.90 | GBA2 (0.42) | GBA2GBA1MEN1KMT2APOLB | |
| SCHEMBL26050252 | 0.90 | GBA1 (0.45) | GBA2GBA1 | |
| SCHEMBL4083012 | 0.84 | GBA2 (0.43) | GBA2GBA1MEN1KMT2APOLB | |
| SCHEMBL4518775 | 0.81 | BCHE (0.37) | GBA2KCNH2NR1I2ALDH1A1 | |
| SCHEMBL21618579 | 0.78 | POLB (0.35) | POLB | |
| SCHEMBL9863071 | 0.75 | GBA1 (0.48) | GBA2GBA1KCNH2 | |
| SCHEMBL5701883 | 0.75 | GBA2 (0.45) | GBA2GBA1MEN1KMT2APOLB | |
| SCHEMBL5702265 | 0.75 | GBA2 (0.45) | GBA2GBA1MEN1KMT2APOLB | |
| SCHEMBL5015303 | 0.74 | GBA1 (0.41) | GBA2GBA1 | |
| SCHEMBL4523595 | 0.74 | SMN1; SMN2 (0.37) | GBA2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234030-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |