Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050348 | 0.90 | GBA2 (0.47) | GBA1GBA2 | |
| SCHEMBL5015303 | 0.83 | GBA1 (0.41) | GBA1GBA2SMN1; SMN2HTR1AKCNK3 | |
| SCHEMBL21618579 | 0.81 | POLB (0.35) | — | |
| SCHEMBL9340416 | 0.80 | GBA2 (0.42) | GBA1GBA2SMN1; SMN2 | |
| SCHEMBL16207902 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL7700224 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2 | |
| SCHEMBL4518775 | 0.75 | BCHE (0.37) | GBA2SMN1; SMN2 | |
| SCHEMBL4083012 | 0.74 | GBA2 (0.43) | GBA1GBA2 | |
| SCHEMBL1545232 | 0.74 | GBA1 (0.50) | GBA1 | |
| SCHEMBL26136282 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234030-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |