SCHEMBL26050416

SCHEMBL26050416

CC1(C)c2cc(-c3ccc(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)cc3)ccc2-c2ccc(-c3ccc(-c4c(-c5ccc(B6OC(C)(C)C(C)(C)O6)cc5)ncnc4-c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)cc3)cc21

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 8/20 0.43
LPL P06858 7/20 0.43
DGAT1 O75907 1/20 0.34
PDGFRB P09619 1/20 0.32
KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26050385 0.89 LIPG (0.54) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL17143469 0.86 LIPG (0.57) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL17143472 0.86 LIPG (0.57) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL24257896 0.86 LIPG (0.57) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL24257893 0.84 PDK2 (0.40)
SCHEMBL12781960 0.82 LIPG (0.62) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL13414973 0.80 LIPG (0.63) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL12781939 0.80 LIPG (0.59) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL24626597 0.79 LIPG (0.57) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL17143221 0.79 LIPG (0.59) LIPGLPLDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271989-A1 METAL COMPLEXES AP3M1, AP1M1, AP2M1 LIPG 3694/4885LPL 3235/4885DGAT1 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.