SCHEMBL13414973

SCHEMBL13414973

CC1(C)OB(c2ccc(C3(c4ccccc4)c4cc(-c5ccccc5)ccc4-c4ccc(-c5ccccc5)cc43)cc2)OC1(C)C

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 13/20 0.63
LPL P06858 12/20 0.63
DGAT1 O75907 1/20 0.38
P4HB P07237 1/20 0.37
PDK2 Q15119 1/20 0.36
PDGFRB P09619 1/20 0.35
KDR P35968 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
SNCA P37840 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12781960 0.97 LIPG (0.62) LIPGLPLDGAT1P4HBPDK2
SCHEMBL12781939 0.95 LIPG (0.59) LIPGLPLDGAT1P4HBPDK2
SCHEMBL2618790 0.95 LIPG (0.59) LIPGLPLDGAT1P4HBPDK2
SCHEMBL12781966 0.94 LIPG (0.55) LIPGLPLDGAT1P4HBPDK2
SCHEMBL24257896 0.94 LIPG (0.57) LIPGLPLDGAT1P4HBPDK2
SCHEMBL17143472 0.94 LIPG (0.57) LIPGLPLDGAT1P4HBPDK2
SCHEMBL17143469 0.94 LIPG (0.57) LIPGLPLDGAT1P4HBPDK2
SCHEMBL12781953 0.92 LIPG (0.52) LIPGLPLDGAT1P4HBPDK2
SCHEMBL26050385 0.90 LIPG (0.54) LIPGLPLDGAT1P4HBPDK2
SCHEMBL13414970 0.90 LIPG (0.67) LIPGLPLDGAT1P4HBPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318948-B2 Fluorene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
US-8318948-B2 Fluorene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, FTO LIPG 1909/4885LPL 2451/4885DGAT1 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.