Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359310 | 0.74 | PTGS2 (0.34) | MAPK14BRD4KMT2AL3MBTL1MEN1 | |
| Arry-797 SCHEMBL29349798 | 0.72 | MAPK14 (1.00) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| SCHEMBL31371662 | 0.72 | MAPK14 (0.69) | MAPK14BRD4ACKR3SMN1; SMN2ALDH1A1 | |
| Arry-797 SCHEMBL31046796 | 0.72 | MAPK14 (1.00) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| Arry-797 SCHEMBL222635 | 0.72 | MAPK14 (1.00) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| Arry-797 SCHEMBL29351662 | 0.72 | MAPK14 (1.00) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| SCHEMBL31371546 | 0.71 | MAPK14 (0.61) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| SCHEMBL21038023 | 0.71 | MAPK14 (0.61) | MAPK14BRD4ACKR3KMT2AL3MBTL1 | |
| SCHEMBL30231342 | 0.71 | ACKR3 (0.69) | MAPK14ACKR3L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31371686 | 0.71 | MAPK14 (0.85) | MAPK14BRD4ACKR3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263803-A1 | METHODS OF PREVENTING OR TREATING COVID-19 AND RELATED VIRAL DISEASES OR DISORDERS | KINARUS AG (CH) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263803-A1 | METHODS OF PREVENTING OR TREATING COVID-19 AND RELATED VIRAL DISEASES OR DISORDERS | PPARA, PPARD, PPARG | MAPK14 85/4885BRD4 365/4885ACKR3 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.