Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26052008 | 0.83 | PDE1A (0.31) | — | |
| SCHEMBL26052151 | 0.83 | GSR (0.39) | — | |
| SCHEMBL26671795 | 0.80 | HRH3 (0.39) | — | |
| SCHEMBL26671801 | 0.80 | NR3C1 (0.32) | — | |
| SCHEMBL23109050 | 0.77 | EPHB3 (0.39) | — | |
| SCHEMBL26671829 | 0.77 | DRD4 (0.44) | NPC1RAB9A | |
| SCHEMBL26052153 | 0.76 | MAPT (0.49) | SMN1; SMN2 | |
| SCHEMBL10499639 | 0.76 | TRPA1 (0.38) | MEN1NPC1RAB9AKMT2AKLF5 | |
| SCHEMBL21849298 | 0.76 | KCNH2 (0.37) | — | |
| SCHEMBL24370198 | 0.76 | EPHB3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |