Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 5/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053265 | 0.92 | HPGD (0.46) | UBE2MDCUN1D1ALDH1A1HPGDRAB9A | |
| SCHEMBL26054887 | 0.87 | UBE2M (0.39) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL26055111 | 0.86 | UBE2M (0.35) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL31595722 | 0.86 | UBE2M (0.35) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL26055110 | 0.86 | UBE2M (0.38) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL26053858 | 0.86 | UBE2M (0.42) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL31699119 | 0.84 | RAB9A (0.42) | ALDH1A1HPGDRAB9APKMTSHR | |
| SCHEMBL31700078 | 0.84 | RAB9A (0.42) | ALDH1A1HPGDRAB9APKMTSHR | |
| SCHEMBL31595868 | 0.84 | UBE2M (0.36) | UBE2MDCUN1D1ALDH1A1GAAGFER | |
| SCHEMBL26058533 | 0.84 | UBE2M (0.36) | UBE2MDCUN1D1ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |