Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18195534 | 0.88 | CTNNB1 (0.61) | CTNNB1NPSR1L3MBTL1MAPTLMNA | |
| SCHEMBL11604077 | 0.81 | CTNNB1 (0.51) | CTNNB1L3MBTL1MAPTLMNAPNLIP | |
| SCHEMBL30775034 | 0.81 | HTT (0.59) | CTNNB1MAPTLMNAPNLIPCYP1A2 | |
| SCHEMBL366 | 0.81 | HTT (0.59) | CTNNB1MAPTLMNAPNLIPCYP1A2 | |
| SCHEMBL6368241 | 0.80 | CTNNB1 (0.74) | CTNNB1L3MBTL1MAPTLMNAPNLIP | |
| SCHEMBL2782639 | 0.80 | CTNNB1 (0.50) | CTNNB1NPSR1L3MBTL1CASP1MAPT | |
| Bromide SCHEMBL2782643 | 0.80 | HTT (0.57) | CTNNB1MAPTLMNAPNLIPCYP1A2 | |
| SCHEMBL855233 | 0.79 | MAPT (0.57) | NPSR1MAPTELANEHTTRAB9A | |
| SCHEMBL4382990 | 0.79 | CYP1A2 (0.65) | CTNNB1NPSR1MAPTLMNACYP1A2 | |
| SCHEMBL432 | 0.79 | MEN1 (0.56) | CTNNB1NPSR1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | CTNNB1 4014/4885NPSR1 4609/4885L3MBTL1 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.