SCHEMBL26054858

SCHEMBL26054858

c1ccc(-c2ccc(N(c3ccc4c(ccc5ccccc54)c3)c3ccc4c(ccc5c6ccccc6ccc45)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.48
ALDH1A1 P00352 4/20 0.45
CYP1B1 Q16678 4/20 0.45
HSD17B10 Q99714 3/20 0.45
HIF1A Q16665 1/20 0.45
TSHR P16473 2/20 0.41
CYP2A6 P11509 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 4/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
MAPT P10636 3/20 0.38
CYP1A1 P04798 3/20 0.38
HPGD P15428 2/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
PAX8 Q06710 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24372522 1.00 HPRT1 (0.48) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL26054860 0.98 HPRT1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL26851472 0.98 HPRT1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL26054798 0.98 HPRT1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL20466406 0.98 ALDH1A1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL24372489 0.98 ALDH1A1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL20466402 0.98 ALDH1A1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL24029722 0.97 HPRT1 (0.45) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL24029728 0.97 HPRT1 (0.45) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A
SCHEMBL26054861 0.97 ALDH1A1 (0.47) HPRT1ALDH1A1CYP1B1HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed