SCHEMBL26054861

SCHEMBL26054861

c1ccc(-c2ccc(N(c3ccc4c(ccc5c6ccccc6ccc45)c3)c3ccc4ccc5ccccc5c4c3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
CYP1B1 Q16678 2/20 0.47
HIF1A Q16665 1/20 0.47
HPRT1 P00492 4/20 0.45
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 3/20 0.38
HPGD P15428 2/20 0.38
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
MAPT P10636 2/20 0.36
CYP1A1 P04798 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26054259 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL24029722 0.97 HPRT1 (0.45) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL24029728 0.97 HPRT1 (0.45) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26054258 0.97 HPRT1 (0.48) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL24372522 0.97 HPRT1 (0.48) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26054858 0.97 HPRT1 (0.48) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL24372508 0.97 HPRT1 (0.48) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26046053 0.95 HPRT1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26054798 0.95 HPRT1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26851307 0.95 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed