SCHEMBL26055488

SCHEMBL26055488

COc1cc(CC(C)N)cc2c1SCO2

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HTR2A P28223 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26055487 0.80 HTR2A (0.50) TAAR1HTR2A
SCHEMBL5305466 0.74 ALDH1A1 (0.48) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL217047 0.74 CYP3A4 (0.62) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL31166209 0.74 ALDH1A1 (0.48) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL29827751 0.74 CYP3A4 (0.62) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL1739571 0.74 CYP3A4 (0.62) TAAR1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL31545549 0.73 CYP3A4 (0.61) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL26055611 0.73 HTR2A (0.38) TAAR1HTR2A
SCHEMBL29633056 0.72 HTR2A (0.54) TAAR1HTR2A
SCHEMBL20970853 0.72 HTR2A (0.54) TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023156453-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2023-08-24 WO disclosed