SCHEMBL20970853

SCHEMBL20970853

COc1cc2c(cc1CC(C)N)OCS2

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.54
TAAR1 Q96RJ0 3/20 0.51
HTR1A P08908 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633056 1.00 HTR2A (0.54) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5473376 0.94 HTR2A (0.54) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL25370278 0.80 TAAR1 (0.49) HTR2ATAAR1HTR2CHTR2B
SCHEMBL2560485 0.79 HTR2A (0.64) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL29417349 0.79 HTR2A (0.64) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5479509 0.72 HTR2A (0.54) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL26055488 0.72 TAAR1 (0.42) HTR2ATAAR1
SCHEMBL398581 0.71 HTR2A (1.00) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL29425260 0.71 HTR2A (1.00) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL398580 0.71 HTR2A (1.00) HTR2ATAAR1HTR1AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630504-B2 Phenethylamine derivatives, compositions, and methods of use CYBIN IRL LIMITED (IE) 2026-05-19 US disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same Park City Bio, LLC (US) 2025-12-11 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2025-09-18 US disclosed
US-12414936-B2 Compositions comprising a serotonergic tryptamine compound CAAMTECH, INC. (US) 2025-09-16 US disclosed
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression Kuleon, LLC (US) 2025-07-01 US disclosed
EP-4251139-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE Wesana Health Inc. (US) 2023-10-04 EP disclosed
US-20230265045-A1 PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-08-24 US disclosed
WO-2023156453-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2023-08-24 WO disclosed
WO-2023156453-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2023-08-24 WO disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 US disclosed
US-20230157997-A9 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2023-05-25 US disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-25 US disclosed
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-11 US disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885TAAR1 84/4885HTR1A 5/4885
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same HTR1A, HTR4, HTR5A HTR2A 8/4885TAAR1 83/4885HTR1A 1/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 HTR2A 6/4885TAAR1 46/4885HTR1A 5/4885
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME HTR5A, HTR1A, HTR3A HTR2A 5/4885TAAR1 77/4885HTR1A 2/4885
US-12630504-B2 Phenethylamine derivatives, compositions, and methods of use HTR2C, HTR1A, HTR2A HTR2A 3/4885TAAR1 41/4885HTR1A 2/4885
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885TAAR1 157/4885HTR1A 5/4885
US-12414936-B2 Compositions comprising a serotonergic tryptamine compound HTR3A, HTR2A, HTR5A HTR2A 2/4885TAAR1 157/4885HTR1A 5/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR2A 19/4885TAAR1 51/4885HTR1A 22/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A HTR2A 1/4885TAAR1 48/4885HTR1A 4/4885
US-20230157997-A9 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885TAAR1 157/4885HTR1A 5/4885
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885TAAR1 157/4885HTR1A 5/4885
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR HTR2C, HTR2A, HTR3B HTR2A 2/4885TAAR1 32/4885HTR1A 9/4885
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression HTR2A, HTR2C, HTR3A HTR2A 1/4885TAAR1 48/4885HTR1A 4/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 HTR2A 14/4885TAAR1 77/4885HTR1A 2/4885
US-20230265045-A1 PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS PNMT, HTR2C, HTR2A HTR2A 3/4885TAAR1 66/4885HTR1A 12/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D HTR2A 16/4885TAAR1 175/4885HTR1A 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.