Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449220 | 0.76 | CYP1A2 (0.39) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL24859351 | 0.76 | ALDH1A1 (0.44) | CYP2A6L3MBTL1CYP1A2ALDH1A1HIF1A | |
| SCHEMBL24175934 | 0.76 | CYP2A6 (0.47) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8220621 | 0.74 | POLB (0.31) | — | |
| SCHEMBL15853168 | 0.73 | ALDH1A1 (0.44) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL16219581 | 0.72 | CYP1A2 (0.35) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL29195181 | 0.72 | POLB (0.39) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL11298213 | 0.72 | PTPN22 (0.42) | HPRT1CYP2A6L3MBTL1ALDH1A1HIF1A | |
| SCHEMBL17030754 | 0.71 | TRPM4 (0.47) | CYP2A6CYP1A2ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL24176031 | 0.71 | AKR1C3 (0.35) | HPRT1CYP2A6L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | HPRT1 2235/4885CYP2A6 3692/4885L3MBTL1 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.