Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449220 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP2A6HPRT1TSHRALDH1A1 | |
| SCHEMBL16219575 | 0.80 | ALDH1A1 (0.46) | HPRT1GPR84ALDH1A1HPGDKDM4E | |
| SCHEMBL14297119 | 0.78 | KDM4E (0.35) | CYP1A2CYP2A6HPRT1ALDH1A1HPGD | |
| SCHEMBL16219583 | 0.75 | ALDH1A1 (0.34) | CYP1A2CYP2A6GPR84TSHRALDH1A1 | |
| SCHEMBL16222598 | 0.75 | ALDH1A1 (0.48) | CYP1A2CYP2A6HPRT1GPR84ALDH1A1 | |
| SCHEMBL24446570 | 0.74 | CYP2A6 (0.46) | CYP1A2CYP2A6HPRT1TSHRALDH1A1 | |
| SCHEMBL26058913 | 0.72 | HPRT1 (0.35) | CYP1A2CYP2A6HPRT1TSHRALDH1A1 | |
| SCHEMBL12017092 | 0.72 | CYP2A6 (0.43) | CYP1A2CYP2A6HPRT1TSHRALDH1A1 | |
| SCHEMBL24859351 | 0.69 | ALDH1A1 (0.44) | CYP1A2CYP2A6TSHRALDH1A1HSD17B10 | |
| SCHEMBL12583259 | 0.69 | MBNL1 (0.42) | CYP1A2CYP2A6GPR84TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9441059-B2 | Metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20140378637-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL SCIENCE FOUNDATION | 2014-12-25 | — | — | US | disclosed |
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | TERT, CYP19A1, MPO | CYP1A2 22/4885CYP2A6 165/4885HPRT1 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.