SCHEMBL26059488

SCHEMBL26059488

c1ccc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccc8c9ccccc9n(-c9ccccc9)c8n7)c6c54)nc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
MAPK8 P45983 2/20 0.39
MAPK9 P45984 1/20 0.39
MAPK1 P28482 2/20 0.36
HTT P42858 2/20 0.36
HKDC1 Q2TB90 1/20 0.35
KMT2A Q03164 2/20 0.34
IL1R1 P14778 1/20 0.34
MAT2A P31153 1/20 0.34
PGR P06401 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19342701 0.86 KDM4E (0.44) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL10027552 0.84 L3MBTL1 (0.55) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL19359947 0.83 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL12792229 0.83 KDM4E (0.50) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL10027536 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL18546820 0.82 KDM4E (0.46) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL10205984 0.82 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL10027549 0.81 KDM4E (0.47) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10205981 0.80 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPK8MAPK9
SCHEMBL10206007 0.79 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032323-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240032323-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20230363190-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-09 US disclosed
US-20230363190-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-09 US disclosed
EP-4235831-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-08-30 EP disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41, EPB41L2 L3MBTL1 877/4885KDM4E 1097/4885ATM 3975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.