SCHEMBL260599

SCHEMBL260599

CC(C)(Br)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.34
GLA P06280 1/20 0.33
PARL Q9H300 1/20 0.32
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14898349 0.88 MGLL (0.31) MGLL
SCHEMBL13447721 0.86 MGLL (0.33) MGLLGLAPARL
SCHEMBL12285677 0.84 POLB (0.31) POLBGAANPSR1
SCHEMBL17777287 0.83 MGLL (0.33) MGLLGLA
SCHEMBL2570463 0.83 MGLL (0.33) MGLLGLA
SCHEMBL6699078 0.83 MGLL (0.33) MGLLGLAPOLBGAANPSR1
SCHEMBL7924643 0.82 MGLL (0.32) MGLLGLA
SCHEMBL12045573 0.80 POLB (0.37) POLBGAANPSR1
SCHEMBL23619542 0.80 MGLL (0.34) MGLLKMT2AATM
SCHEMBL17664956 0.80 MGLL (0.31) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708446-B2 Polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-25 US claimed
CN-111072877-B Method for self-assembling protein conjugate into nano-microsphere by polymerization initiation 南京理工大学 2022-03-22 CN claimed
US-20210221937-A1 POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-07-22 US claimed
US-11041026-B2 Reactions enabled by thermoresponsive and photoresponsive gels MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-22 US claimed
CN-112618803-A Preparation method of temperature response type bionic nanocone dual-functional antibacterial surface 大连理工大学 2021-04-09 CN claimed
CN-108976362-B Method for non-genetic modification of microorganisms based on phase transition lysozyme nano-film 陕西师范大学 2020-11-17 CN claimed
CN-111072877-A Method for self-assembling protein conjugate into nano-microsphere by polymerization initiation 南京理工大学 2020-04-28 CN claimed
WO-2018140977-A1 REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-08-02 WO claimed
US-20120016082-A1 CONJUGATION REACTIONS BIOCOMPATIBLES UK LIMITED (GB) 2012-01-19 US claimed
EP-1592719-B1 CONJUGATION REACTIONS BIOCOMPATIBLES UK LTD (GB) 2008-03-26 EP claimed
US-20060135714-A1 Conjugation reactions BIOCOMPATIBLES UK LIMITED (GB) 2006-06-22 US claimed
EP-1592719-A1 CONJUGATION REACTIONS Biocompatibles UK Limited (GB) 2005-11-09 EP claimed
WO-2004063237-A1 CONJUGATION REACTIONS BIOCOMPATIBLES UK LIMITED (GB) 2004-07-29 WO claimed
US-20260007755-A1 SELF-ASSEMBLED DIBLOCK COPOLYMERS COMPOSED OF PEGMEMA AND DRUG BEARING POLYMERIC SEGMENTS RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET ANONIM SIRKETI (TR) 2026-01-08 US disclosed
US-12427199-B2 Self-assembled diblock copolymers composed of pegmema and drug bearing polymeric segments RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET ANONIM SIRKETI (TR) 2025-09-30 US disclosed
EP-3935149-B1 METHOD FOR SEPARATING CELLS USING A TEMPERATURE-RESPONSIVE POLYMER UNIV SIEGEN (DE) 2025-04-23 EP disclosed
US-20080300348-A1 Polymer WARWICK EFFECT POLYMERS LIMITED 2008-12-04 US disclosed
WO-2007100902-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION OLIGASIS CORPORATION (US) 2007-09-07 WO disclosed
EP-1646661-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUNG OBTAINED THEREFROM Warwick Effect Polymers Limited (GB) 2006-04-19 EP disclosed
WO-2004113394-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUGS OBTAINED THEREFROM WARWICK EFFECT POLYMERS LIMITED (GB) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007755-A1 SELF-ASSEMBLED DIBLOCK COPOLYMERS COMPOSED OF PEGMEMA AND DRUG BEARING POLYMERIC SEGMENTS CLTB, F13B, FGB MGLL 3400/4885GLA 703/4885PARL 2264/4885
US-20120016082-A1 CONJUGATION REACTIONS PHPT1, GNE, MGMT MGLL 4388/4885GLA 3819/4885PARL 3968/4885
US-12427199-B2 Self-assembled diblock copolymers composed of pegmema and drug bearing polymeric segments BCR, EGFR, PBRM1 MGLL 3293/4885GLA 2674/4885PARL 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.