Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26061355 | 1.00 | HDAC6 (0.35) | HDAC6HDAC3HDAC1HDAC2PRMT5 | |
| SCHEMBL26051962 | 0.94 | HDAC6 (0.35) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL26051963 | 0.94 | HDAC6 (0.35) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL26056274 | 0.89 | HDAC6 (0.36) | HDAC6HDAC3HDAC1HDAC2PRMT5 | |
| SCHEMBL26061353 | 0.89 | HDAC6 (0.36) | HDAC6HDAC3HDAC1HDAC2PRMT5 | |
| SCHEMBL26056262 | 0.84 | HDAC6 (0.38) | HDAC6HDAC3HDAC1HDAC2CCR2 | |
| SCHEMBL26051957 | 0.83 | P2RX3 (0.35) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL26051960 | 0.83 | P2RX3 (0.35) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL26055860 | 0.83 | — | — | |
| SCHEMBL26055854 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |