SCHEMBL26061868

SCHEMBL26061868

CC(F)(F)C(F)(F)C(F)(F)C(=O)Oc1ccc(O)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ ELANE P08246 8/20 0.37
▸ ATM Q13315 2/20 0.35
▸ NR1H4 Q96RI1 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ ESR1 P03372 2/20 0.34
▸ ESR2 Q92731 2/20 0.34
▸ MIF P14174 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26061870 0.83 VCAM1 (0.39) POLBMAPTCA1CA2ELANE
SCHEMBL19335493 0.83 ELANE (0.55) POLBMAPTCA2ELANE
SCHEMBL26061849 0.81 ELANE (0.53) MAPTELANEGAAXBP1
SCHEMBL26061853 0.81 ELANE (0.47) ELANEATMGAA
SCHEMBL15294396 0.78 ELANE (0.43) POLBMAPTELANEATMNR1H4
SCHEMBL26061855 0.76 CYP4F2 (0.39) MAPTCA1CA2ELANE
SCHEMBL26061847 0.74 ELANE (0.47) MAPTELANEATML3MBTL1
SCHEMBL377567 0.74 CYP3A4 (0.52) POLBMAPTCA2ELANEGAA
SCHEMBL25788215 0.74 ELANE (0.49) CA1CA2ELANE
SCHEMBL25788248 0.72 AKR1C3 (0.47) POLBELANEGAAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739056-B2 Carboxylate, carboxylic acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739056-B2 Carboxylate, carboxylic acid generator, resist composition and method for producing resist pattern CHRM1, CHRM2, SCO2 POLB 838/4885MAPT 4650/4885CA1 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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