Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25892891 | 0.89 | TSHR (0.46) | TSHRSMN1; SMN2HPGDTLR2FAAH | |
| SCHEMBL23729612 | 0.88 | FAAH (0.43) | TSHRSMN1; SMN2HPGDTLR2FAAH | |
| SCHEMBL26708614 | 0.88 | FAAH (0.43) | TSHRSMN1; SMN2HPGDTLR2FAAH | |
| SCHEMBL25029533 | 0.87 | TSHR (0.51) | TSHRSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL2625059 | 0.84 | TSHR (0.49) | TSHRSMN1; SMN2HPGDTLR2FAAH | |
| SCHEMBL25029949 | 0.83 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2HPGDKMT2AHSD17B10 | |
| SCHEMBL12214864 | 0.81 | TSHR (0.49) | TSHRSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL26724992 | 0.81 | PAOX (0.40) | TSHRTLR2ALDH1A1 | |
| SCHEMBL18959180 | 0.80 | TSHR (0.54) | TSHRSMN1; SMN2FAAHCNR1RECQL | |
| SCHEMBL16071577 | 0.80 | TSHR (0.54) | TSHRSMN1; SMN2HPGDFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161874-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |