Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26708614 | 1.00 | FAAH (0.43) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL26063007 | 0.88 | TSHR (0.50) | FAAHTSHRHPGDSMN1; SMN2NAMPT | |
| SCHEMBL26700903 | 0.87 | FAAH (0.42) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL26700902 | 0.87 | FAAH (0.42) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL23730062 | 0.87 | HPGD (0.46) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL23729791 | 0.87 | TSHR (0.44) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL25892891 | 0.86 | TSHR (0.46) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL26708617 | 0.85 | TSHR (0.42) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL26700763 | 0.85 | TSHR (0.42) | FAAHTSHRHPGDCASP2SMN1; SMN2 | |
| SCHEMBL26708162 | 0.85 | TSHR (0.42) | FAAHTSHRHPGDCASP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |