Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606368 | 0.93 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2606370 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2606472 | 0.88 | SMN1; SMN2 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2606356 | 0.88 | S1PR3 (0.40) | L3MBTL1CNR2GCKSMN1; SMN2RAB9A | |
| SCHEMBL1000101 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1GCKSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL999977 | 0.86 | FPR2 (0.40) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL999595 | 0.86 | GCK (0.40) | GCK | |
| SCHEMBL2606337 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL998812 | 0.80 | CDK2 (0.39) | — | |
| SCHEMBL998383 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444397-A1 | Heteroaryl-ureas and their use as glucokinase activators | Novo Nordisk A/S (DK) | 2012-04-25 | — | — | EP | disclosed |