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SCHEMBL26065348

SCHEMBL26065348

Cc1nc(C(F)F)ccc1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 14/20 0.49
▸ F13A1 P00488 11/20 0.49
▸ TGM1 P22735 8/20 0.49
▸ TGM3 Q08188 1/20 0.47
▸ LMNA P02545 2/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ EPHX2 P34913 1/20 0.43
▸ GPR119 Q8TDV5 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25370533 0.87 F13A1 (0.37) TGM2F13A1TGM1TGM3EPHX2
SCHEMBL26066135 0.86 TGM2 (0.46) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065641 0.85 TGM2 (0.46) TGM2F13A1TGM1TGM3EPHX2
SCHEMBL26065416 0.85 TGM2 (0.48) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065393 0.83 TGM2 (0.53) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065252 0.83 TGM2 (0.53) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065734 0.83 TGM2 (0.53) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065927 0.83 TGM2 (0.52) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065932 0.80 TGM2 (0.57) TGM2F13A1TGM1TGM3LMNA
SCHEMBL26065937 0.80 TGM2 (0.47) TGM2F13A1TGM1TGM3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO disclosed