SCHEMBL26065641

SCHEMBL26065641

CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(C(F)F)nc2C2CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 14/20 0.46
F13A1 P00488 11/20 0.46
TGM1 P22735 8/20 0.46
GPR119 Q8TDV5 5/20 0.44
TGM3 Q08188 1/20 0.44
EPHX2 P34913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25370862 0.88 GPR119 (0.38) TGM2F13A1TGM1GPR119EPHX2
SCHEMBL26065348 0.85 TGM2 (0.49) TGM2F13A1TGM1GPR119TGM3
SCHEMBL26066077 0.84 TGM2 (0.49) TGM2F13A1TGM1GPR119TGM3
SCHEMBL26066135 0.82 TGM2 (0.46) TGM2F13A1TGM1TGM3
SCHEMBL26065642 0.77 CYP3A4 (0.40)
SCHEMBL26065648 0.76 SMN1; SMN2 (0.40)
SCHEMBL26065637 0.74 NAMPT (0.38)
SCHEMBL25370533 0.73 F13A1 (0.37) TGM2F13A1TGM1GPR119TGM3
SCHEMBL26065416 0.73 TGM2 (0.48) TGM2F13A1TGM1GPR119TGM3
SCHEMBL25371714 0.73 GPR119 (0.40) TGM2F13A1TGM1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 WO disclosed