Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066057 | 0.90 | KCNH2 (0.43) | TRPV4NPC1CNR1CNR2ALDH1A1 | |
| SCHEMBL26065808 | 0.90 | TRPV4 (0.40) | TRPV4NPC1CNR1CNR2ALDH1A1 | |
| SCHEMBL26065205 | 0.89 | SMN1; SMN2 (0.43) | TRPV4NPC1CNR1CNR2ALDH1A1 | |
| SCHEMBL25372556 | 0.88 | TRPV4 (0.40) | TRPV4CASP3OPRM1SIGMAR1SMN1; SMN2 | |
| SCHEMBL26065214 | 0.85 | KDM4E (0.41) | TRPV4CNR1CNR2ALDH1A1KDM4E | |
| SCHEMBL26065772 | 0.84 | TRPV4 (0.40) | TRPV4ALDH1A1GAACYP3A4CYP2D6 | |
| SCHEMBL26065337 | 0.83 | POLB (0.36) | TRPV4NPC1CNR1CNR2ALDH1A1 | |
| SCHEMBL26065199 | 0.82 | TRPV4 (0.37) | TRPV4CNR1CNR2ALDH1A1GAA | |
| SCHEMBL25371694 | 0.82 | TRPV4 (0.34) | TRPV4CNR1CNR2CASP3SMN1; SMN2 | |
| SCHEMBL26065760 | 0.81 | CNR1 (0.37) | TRPV4CNR1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |