Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 5/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065180 | 0.90 | TRPV4 (0.38) | TRPV4ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL27346583 | 0.90 | TRPV4 (0.40) | TRPV4BRS3CXCR3 | |
| SCHEMBL30719473 | 0.90 | TRPV4 (0.40) | TRPV4BRS3CXCR3 | |
| SCHEMBL25370981 | 0.89 | TRPV4 (0.38) | TRPV4BRS3 | |
| SCHEMBL30567105 | 0.89 | TRPV4 (0.38) | TRPV4BRS3 | |
| SCHEMBL26065772 | 0.83 | TRPV4 (0.40) | TRPV4ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL26065732 | 0.82 | TRPV4 (0.39) | TRPV4ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL26066057 | 0.81 | KCNH2 (0.43) | TRPV4ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL26065201 | 0.80 | KMT2A (0.38) | TRPV4ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL26065808 | 0.80 | TRPV4 (0.40) | TRPV4ALDH1A1CYP3A4GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |